About Us

Who We Are

Eight million Americans with diabetic retinopathy require injections directly into the eye. However, current therapies cannot be used in early disease and fail in many of patients. Skyran Biologics has a better option: an eye drop to treat all DR pathologies.

With robust animal data demonstrating anti-angiogenic, anti-inflammatory, and neuroprotective properties, an issued US patent, and seed money, Skyran is ready to complete IND-enabling studies.

Skyran uses technology generated at the Penn State College of Medicine (http://med.psu.edu/medical-innovation) by Drs. Joyce Tombran-Tink and Colin Barnstable. The company is a participant in the Phase 1 Ventures program of the University City Science Center (https://www.sciencecenter.org/discover/phase-1-ventures), which give us access to matching funds, a number of services, and the Philadelphia life sciences entrepreneurial community.

Meet the Skyran Team

Dr. Joyce Tombran-Tink

Founder, Skyran Biologics, Inc.

Bio

Dr. Tombran-Tink has been a Professor in the Department of Neural and Behavioral Sciences and Ophthalmology at the Penn State College of Medicine since 2007. 

She received her PhD in cell and molecular biology at the University of Southern California and was awarded the Fight For Sight Citation Award for the discovery of Pigment Epithelial Derived factor (PEDF), a neurotrophic factor in the eye, by the Association for Research in Vision and Ophthalmology (ARVO). She was subsequently awarded a National Research Council Fellowship and a Staff Fellowship at the National Institutes of Health where she served for 7 years. She also served on the faculty of the Children’s National Medical Center, George Washington University, University of Missouri, and Yale University. She is a gold Fellow of ARVO and has served as a member of the Board of Governors for the ARVO Foundation for the past six years.

Dr. Tombran-Tink has served as a consultant for the Collaborative Research and Development Foundation Global for the past twenty-one years. She has published over 90 peer-reviewed articles and book chapters, served as co-Editor-in-Chief for the Journal of Ocular Biology Diseases and Informatics, as co-editor for a series of eight textbooks in Ophthalmology, and on the editorial boards of several research journals. Dr. Tombran-Tink is an inventor on several patents for the use of PEDF and generation of PEDF peptide mimetics for neurodegenerative diseases including diabetic retinopathy.

Dr. Colin Barnstable

Founder, Skyran Biologics, Inc.

Bio

Dr. Barnstable has served as Professor and Chair of the Department of Neural and Behavioral Sciences at Penn State College of Medicine and Research Director of the Penn State Hershey Eye Center since 2006.

He received his B.A. in biochemistry and his D.Phil. in genetics from the University of Oxford and then moved to Harvard as a postdoctoral fellow for 2 years. After three years on the faculty of Harvard Medical School he spent five years as a faculty member of the Rockefeller University. From 1988 to 2006 he was a faculty member of the Departments of Ophthalmology and Visual Sciences, and Neurobiology, at Yale University School of Medicine and Research Director of the Yale Eye Center. He has served on the editorial boards of numerous neuroscience and eye research journals and a variety of NIH study sections. Dr. Barnstable has published over 190 articles and reviews and is co-editor (with Dr. Tombran-Tink) of a series of textbooks on Ophthalmology.